The 7-Point Tested Standard. Every batch of every Nexura Labs research peptide is released only after passing seven independent third-party analytical tests. Clean chemistry. Pure batches. Documented every time.
Why we publish every test result
Research-grade peptides are tools that produce data. A vendor’s analytical work is the foundation under any experiment that uses that peptide. We publish every batch’s Certificate of Analysis in our public COA Library — chromatograms, mass spectra, endotoxin results, sterility results, signed and dated by the third-party laboratory — because verifiable analytical work is what separates a research-grade supplier from a marketing label.
The 7-Point panel below is the complete release criteria. No batch ships without passing all seven.
Test #1 — HPLC Purity
Method: Reversed-phase high-performance liquid chromatography (RP-HPLC), UV detection at 214 nm.
What it confirms: The proportion of total UV-absorbing material in the sample that is the target peptide. Target specification: ≥97% purity. The chromatogram is included on every Certificate of Analysis.
Why it matters: HPLC is the standard analytical method referenced in USP General Chapter <621>. A reported purity figure without an attached chromatogram is unverifiable. We publish the chromatogram for every batch.
Test #2 — Mass Spectrometry (Identity)
Method: Mass spectrometry (MS) — molecular weight confirmation against the theoretical mass of the target sequence.
What it confirms: The species in the HPLC peak is the correct molecule. HPLC tells us how much; mass spec tells us what. Together they confirm both purity and identity.
Acceptance criterion: Observed mass within ±0.1 Da of the theoretical molecular weight.
Test #3 — Net Content Accuracy
Method: Quantitative analysis of peptide content per vial.
What it confirms: The labeled mass (e.g., 5 mg, 10 mg, 50 mg) matches the actual peptide content in the vial. Lyophilized peptides include both the active peptide and counter-ions / residual solvents from synthesis; “net peptide content” is the true active mass.
Why it matters: Reproducible analytical chemistry requires accurate dosing of the reference standard. A vial labeled “10 mg” containing 8 mg of active peptide silently breaks every assay built on that label.
Test #4 — Sterility
Method: Sterility testing per pharmacopoeial methods.
What it confirms: The lyophilized vial is free of microbial contamination at the time of release.
Why it matters: Microbial contamination of a research reagent produces uninterpretable assay noise. Sterility is a basic release criterion for any chemistry reference material distributed in solution-ready form.
Test #5 — Endotoxin (LAL)
Method: Limulus Amebocyte Lysate (LAL) assay.
What it confirms: Bacterial endotoxin levels in the lyophilized peptide are below the reporting threshold for research-grade reference material.
Why it matters: Endotoxin is a class of bacterial cell-wall fragments that can persist through synthesis even when no live microorganisms remain. Endotoxin contamination produces inflammatory artifacts in cell-based assays. The LAL test is the standard method for detecting it.
Test #6 — Heavy Metal Screening
Method: Inductively coupled plasma mass spectrometry (ICP-MS) or equivalent trace-metals method.
What it confirms: Concentrations of trace heavy metals (e.g., lead, arsenic, cadmium, mercury) are below research-grade thresholds.
Why it matters: Trace metal contamination from synthesis catalysts or column degradation can interfere with metal-binding assays, redox chemistry, and any analytical work where trace ions are themselves the variable.
Test #7 — Conformity Verification
Method: Final review of batch documentation against the product specification sheet.
What it confirms: All six prior analytical tests have passed; vial labeling, lot number, and packaging match the released batch record; and the Certificate of Analysis is complete, signed, and traceable.
Why it matters: A test result is only useful if it’s tied to the specific vial in your hand. Conformity verification ensures the COA you read corresponds to the batch you receive — not a representative sample from a different production run.
The published evidence
Every batch’s complete 7-Point analytical record is published in our public COA Library. The batch identifier on the vial label maps directly to the COA document — you can verify the analytical work for the exact material you receive, before and after purchase.
Browse our catalog of 7-Point Tested research peptides:
Nexura Labs research peptides are supplied for laboratory and analytical research use only. They are not approved by the FDA and are not intended for human or veterinary consumption, ingestion, or injection.
